Article in Arteriosclerosis, thrombosis, and vascular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Yunhong Zhang *Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0000-0002-5899-5149
Zhen Zhang *Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0009-5573-0629
Xinkui LiuInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0000-0002-0609-6651
Chu ChuInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0000-0003-1050-7780
Wei LiInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0003-6683-9933
Tingting ZhangInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0002-9503-458X
Huiyan ZuInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0004-6297-0106
Nannan FanInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0000-0003-2225-4178
Ran WeiSchool of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China (R.W.).ORCID 0000-0002-9537-8481
Feifei ShiInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0005-5056-989X
Fang LiInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0009-0003-2712-1187
Fei XuDepartment of Respiratory and Critical Care Medicine, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan (F.X.).ORCID 0000-0003-3634-6188
Bin WangThe Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan (B.W.).ORCID 0009-0003-1912-5284
Xia LiInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China (Y.Z., Z.Z., X. Liu, C.C., W.L., T.Z., H.Z., N.F., F.S., F.L., X. Li).ORCID 0000-0001-8938-1206
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundDeep vein thrombosis (DVT) is a prevalent peripheral vascular disorder associated with abnormal epigenetic processes and altered gene expression in endothelial cells. Accumulating evidence has demonstrated that NAT10 (
methodsTo explore the potential mechanism of NAT10 and ferroptosis on thrombogenesis, we used NAT10 and GPX4 (glutathione peroxidase 4) knockout mice as an in vivo model, and utilized techniques, such as RNA immunoprecipitation, acRIP-qPCR (acetylated RNA immunoprecipitation-quantitative PCR),
resultsGPX4 is a pivotal gene that suppresses ferroptosis. Utilizing endothelial cell-specific GPX4 conditional knockout mice (GPX4
conclusionsCollectively, our data elucidate that downregulation of NAT10 mitigates endothelial ferroptosis and prevents DVT formation and progression by modulating HMOX1 expression, which offers a potential novel strategy for the prevention and treatment of thrombosis in DVT.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.