Observational studyJournal of the American Heart Association2026
Subendocardial Viability Ratio Is Associated With Target Organ Damage and Hints at a Potential Independent Predictor of Cardiovascular Mortality in Older Adults: A Prospective Cohort Study.
Observational study in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02368938 (Prognosis Factors of Mortality and Cardiovascular Diseases in the Elderly Chinese), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognosis Factors of Mortality and Cardiovascular Diseases in the Elderly Chinese: the Northern Shanghai Study
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut Microbiota and Its Metabolites in the Prognosis of Coronary Heart Disease: A Systematic Review and Mechanistic Insights.Cardiovascular drugs and therapy · 2026Pooled it
- Clinical Significance of Cardio-Ankle Vascular Index in Stage A/B Heart Failure Patients With Type 2 Diabetes Mellitus.Journal of clinical medicine research · 2026Article
- Cardiovascular risk scores, non-invasive vascular measures and myositis damage index reveal increased cardiovascular risk in idiopathic inflammatory myopathies: a case-control study.BMC rheumatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe subendocardial viability ratio (SEVR) reflects myocardial perfusion relative to workload. This study explored the association of SEVR with mortality and subclinical target organ damage in an older adult population.
methodsWe analyzed the data from the Northern Shanghai Study, a community-based cohort of older adults aged over 65 years. SEVR was measured with arterial tonometry. Cross-sectional associations were assessed between SEVR levels and target organ damage (including arterial stiffness, peripheral artery disease, carotid plaque, left ventricular hypertrophy, left ventricular diastolic dysfunction, chronic kidney dysfunction, and microalbuminuria). Longitudinal associations between SEVR and mortality were evaluated using Cox and Fine-Gray models.
resultsAmong 3237 participants (mean age 71±6 years, 57% female), 233 deaths occurred over a median follow-up of 5.7 years, including 94 cardiovascular deaths. Participants were divided into 2 groups by the median value of SEVR (129%). The group with a lower SEVR (≤129%) was associated with higher risk of cardiovascular death (adjusted
conclusionsLower SEVR is independently associated with both increased cardiovascular mortality and organ damage, including arterial stiffness and left ventricular diastolic dysfunction in older adult populations. SEVR may be a convenient marker for early cardiovascular risk stratification in aging populations. REGISTRATION: URL: https://ClinicalTrial.gov; Unique Identifier: NCT02368938.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.