Evidence map›Paper›PMID 41467845›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2026

Acrolein Promotes Retinal Inflammation Through Macrophage Chemotaxis by Inducing CCL2 Production From Müller Cells.

Kanae Fukutsu, Miyuki Murata, Kasumi Kikuchi, Kousuke Noda, Susumu Ishida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Acrolein Promotes Retinal Inflammation Through Macrophage Chemotaxis by Inducing CCL2 Production From Müller Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kanae FukutsuDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.ORCID 0000-0001-6315-2077
Miyuki MurataDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.ORCID 0009-0006-1918-9562
Kasumi KikuchiDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.ORCID 0009-0005-1804-1788
Kousuke NodaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.ORCID 0000-0002-1281-5026
Susumu IshidaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.ORCID 0000-0001-6686-4168

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 24K12777MEXT | Japan Society for the Promotion of Science (JSPS) 24K19803
6 · The paper itself

Abstract

This study aimed to investigate the inflammatory mechanisms induced by the toxic aldehyde acrolein in proliferative diabetic retinopathy (PDR). N

Indexed as

AcroleinChemokine CCL2ChemotaxisDiabetic RetinopathyEpendymoglial CellsInflammationMacrophagesAnimalsCell LineFemaleHMGB1 ProteinHumansMaleMiceMiddle AgedRatsAcroleinCCL2 protein, humanCcl2 protein, ratChemokine CCL2HMGB1 ProteinacroleinCCL2 proteindiabetic retinopathyHMGB1 proteinMuller cells

Identifiers

PMID41467845
PMCPMC12752455

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.