ArticleJournal of the American Chemical Society2026
DNP-Enhanced Magic Angle Spinning Solid-State NMR Spectroscopy to Determine RNA-Ligand Interactions.
Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- High-frequency dynamic nuclear polarization in rotating solids.Science advances · 2026Review
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9 authors.
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Abstract
Understanding the molecular recognition underlying RNA-ligand complex formation is of key importance to explain the RNA regulatory function of riboswitches and to support the development of low-molecular-weight RNA binders as starting points for the development of RNA-targeting drugs. Here, we report magic angle spinning solid-state NMR spectroscopic studies enhanced by dynamic nuclear polarization (MAS-DNP) to determine the molecular recognition of a ligand-RNA riboswitch complex. We benchmarked different labeling strategies for four large RNAs (70-86 nt) of the aptamer domain of a 2'deoxyguanosine-sensing riboswitch from
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