Evidence map›Paper›PMID 41469802›Full record

ArticleNPJ digital medicine2025

PIC-SURE: an open-source platform for integrating clinical and genomic data.

Alba Gutiérrez-Sacristán, Emily E Hughes, Ryan Amari, George Colon, Thomas N DeSain, Sharra Neely, James T Peck, Samantha Piatt, Lucas Sikina, Jessica Lyons and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alba Gutiérrez-Sacristán *Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Emily E Hughes *Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Ryan AmariDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
George ColonDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Thomas N DeSainDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Sharra NeelyDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
James T PeckDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Samantha PiattComputational Health Informatics Program, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, USA.
Lucas SikinaComputational Health Informatics Program, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, USA.
Jessica LyonsDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Danielle PillionDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA.
Paul AvillachDepartment of Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA, USA. paul_avillach@hms.harvard.edu.

Funding

NHLBI Data Stage Coordinating CenterOT3HL147154 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ashok Kumar Krishnamurthy · 2018 to 2026
$98.9M
The Integration of Trans-omics for Precision Medicine (TOPMED) and Other Heart, Lung, Blood and Sleep (HLBS) Data Sets with the Data CommonsOT3HL142480 · NHLBI · HARVARD MEDICAL SCHOOL · PI AVILLACH, PAUL · 2017 to 2022
$8.8M
Instrumenting the Delivery System for a Genomics Research Information CommonsU01TR002623 · NCATS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2019 to 2024
$8.6M
NCATS NIH HHS 5U01TR002623NCATS NIH HHS U01 TR002623NHLBI NIH HHS 3OT3HL142480NHLBI NIH HHS OT3 HL142480NHLBI NIH HHS OT3 HL147154
6 · The paper itself

Abstract

PIC-SURE is an open-source platform for integrating and analyzing large-scale clinical and genomic data. Part of the NIH NHLBI BioData Catalyst® ecosystem, PIC-SURE enables real-time cohort building and analysis across 1.4 M participants within 273 studies (May 2025). Through a graphical interface and API, researchers can explore and analyze complex datasets in real time. This flexibility supports scalable and reproducible research, lowering the barrier to integrated clinical and genomic data analysis.

Identifiers

PMID41469802
PMCPMC12855934

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.