Evidence map›Paper›PMID 41470199›Full record

ArticleMedicina (Kaunas, Lithuania)2025

Silibinin Triggers Mitochondrial Apoptosis and Declines Clonogenic Potential in Detroit 562 Human Pharyngeal Carcinoma Cells.

Serban Talpos, Doina Chioran, George Cătălin Alexandru, Ștefania Dinu, Elena-Dorina Coricovac, Andreea Smeu, Diana Haj Ali, Camelia Szuhanek, Malina Popa

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Phytochemical Characterization and Biological Assessment ofAntioxidants (Basel, Switzerland) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serban TalposDiscipline of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, Revolutiei Boulevard 9, 300041 Timisoara, Romania.
Doina ChioranDepartment of Anesthesiology and Oral Surgery, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
George Cătălin AlexandruDoctoral School, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square, No.2, 300041 Timisoara, Romania.
Ștefania DinuDepartment of Pedodontics, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 9 No., Revolutiei Bv., 300041 Timisoara, Romania.ORCID 0000-0002-4351-7726
Elena-Dorina CoricovacDepartment of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-5760-8872
Andreea SmeuDepartment of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Diana Haj AliDepartment of Toxicology, Drug Industry, Management and Legislation, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Camelia SzuhanekOrthodontic Research Center ORTHO-CENTER, Discipline of Orthodontics I, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 9 No., Revolutiei Bv., 300041 Timisoara, Romania.ORCID 0000-0002-3668-2299
Malina PopaDepartment of Pedodontics, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, 9 No., Revolutiei Bv., 300041 Timisoara, Romania.ORCID 0000-0001-7286-3161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisMitochondriaPharyngeal NeoplasmsSilybinCell Line, TumorCell SurvivalHumansReactive Oxygen SpeciesReactive Oxygen SpeciesSilybinalternative treatmentgingival fibroblastshuman papillomavirusmitochondrial apoptosisoropharyngeal cancersilibinin

Identifiers

PMID41470199
PMCPMC12735190

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.