Evidence map›Paper›PMID 41470417›Full record

ArticleMaterials (Basel, Switzerland)2025

Biocompatibility of Materials Dedicated to Non-Traumatic Surgical Instruments Correlated to the Effect of Applied Force of Working Part on the Coronary Vessel.

Marcin Dyner, Aneta Dyner, Adam Byrski, Marcin Surmiak, Magdalena Kopernik, Katarzyna Kasperkiewicz, Przemyslaw Kurtyka, Karolina Szawiraacz, Kamila Pietruszewska, Zuzanna Zajac and 5 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marcin DynerFaculty of Science and Technology, Jan Dlugosz University, 42-200 Czestochowa, Poland.
Aneta DynerChirstom Marcin i Marek Dyner S.C., 42-240 Rudniki, Poland.ORCID 0000-0001-7387-7178
Adam ByrskiInstitute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Cracow, Poland.ORCID 0000-0003-1152-5964
Marcin SurmiakDepartment of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, 31-066 Cracow, Poland.ORCID 0000-0001-8396-1488
Magdalena KopernikAGH University of Krakow, 30-059 Cracow, Poland.ORCID 0000-0001-8705-6506
Katarzyna KasperkiewiczInstitute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, 40-032 Katowice, Poland.ORCID 0000-0002-9851-790X
Przemyslaw KurtykaInstitute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Cracow, Poland.ORCID 0000-0001-8692-0737
Karolina SzawiraaczInstitute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Cracow, Poland.ORCID 0000-0002-2466-5766
Kamila PietruszewskaCenter for the Development of Therapies for Civilization and Age-Related Diseases, Jagiellonian University Medical College, 31-066 Cracow, Poland.ORCID 0009-0001-0027-9086
Zuzanna ZajacInstitute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Cracow, Poland.ORCID 0009-0003-5295-7998
Lukasz MuchaFoundation of Cardiac Surgery Development, 41-800 Zabrze, Poland.
Juergen M LacknerInstitute for Sensors, Photonics and Manufacturing Technologies, JOANNEUM RESEARCH Forschungsgesellschaft mbH, 8712 Niklasdorf, Austria.
Michael BererPolymer Competence Center Leoben GmbH, 8700 Leoben, Austria.ORCID 0000-0001-8863-2667
Boguslaw MajorInstitute of Metallurgy and Materials Science, Polish Academy of Sciences, 30-059 Cracow, Poland.
Marcin BasiagaSilesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0001-5978-3861

Funding

Polish National Center for Research and Development; Austrian Federal Ministry - FFG; Scientific and Technological Research Council of Tϋrkiye: Tϋbitak M-ERA.NET3/2022/75/AtraumaBioMat/2023; FO999900377; 123N419
6 · The paper itself

Abstract

Cardiovascular clamping procedures can cause tissue traumatization, leading to serious adverse events interrupting blood flow and causing life-threatening hemorrhage. The aim of the study is to evaluate the properties of 3D-printed, high-elasticity elastomeric materials-BioMed Flex 50A and 80A (Formlabs Inc., Sommerville, MA, USA)-in terms of their suitability for the fabrication of atraumatic inserts used for surgical clamping instruments. To show the importance of the elaboration of the new atraumatic materials, finite element simulations of blood vessel compression by a surgical tool were validated experimentally with porcine vessels, and histopathology assessed the tissue response. These results confirm that excessive clamping forces can cause vessel wall stratification and rupture. Specimens BioMed Flex 50A and 80A underwent surface, mechanical, and biological testing, including topography, wettability, acoustic microscopy for structural voids, cytotoxicity with human dermal fibroblasts, pro-inflammatory marker analysis, and bacterial biofilm assessment. The results of the testing of the 3D-printed BioMed Flex 50A and 80A materials show good potential for applications in safe atraumatic surgical instruments. Further research may include the possibilities to develop 3D-printed metamaterials with pressure adapting properties.

Indexed as

atraumatic surgical instrumentsbiocompatible 3D printing resinscytotoxicity and biofilm resistancemetamaterial-based medical devicesvascular compression modeling

Identifiers

PMID41470417
PMCPMC12734898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.