Evidence map›Paper›PMID 41471059›Full record

ArticlePharmaceutics2025

PopPK and PBPK Models Guide Meropenem Dosing in Critically Ill Children with Augmented Renal Clearance.

Yao Liu, Hua He, Sa-Sa Zhang, Jia Zhou, Jin-Wei Zhu, Jin Xu, Hong-Jun Miao, Ji-Hui Chen, Kun Hao

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yao LiuState Key Laboratory of Natural Medicine, Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0002-9470-6789
Hua HeDepartment of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Sa-Sa ZhangState Key Laboratory of Natural Medicine, Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.
Jia ZhouDepartment of Clinical Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200082, China.
Jin-Wei ZhuState Key Laboratory of Natural Medicine, Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.
Jin XuDepartment of Pharmacy, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.
Hong-Jun MiaoDepartment of Emergency, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.
Ji-Hui ChenDepartment of Clinical Pharmacy, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200082, China.ORCID 0000-0002-9819-9921
Kun HaoState Key Laboratory of Natural Medicine, Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.ORCID 0000-0003-0147-1608

Funding

Jiangsu Pharmaceutical Association A2022218Nanjing Pharmaceutical Association 2024YX002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

meropenemmodel-informed precision dosingpediatric intensive carephysiologically based pharmacokinetic modelpopulation pharmacokinetic modelrenal function

Identifiers

PMID41471059
PMCPMC12736838

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.