ArticlePathogens (Basel, Switzerland)2025
Systemic Inflammatory Indices (SII and SIRI) in 30-Day Mortality Risk Stratification for Community-Acquired Pneumonia: A Study Alongside CURB-65 and PSI.
Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Risk warning of systemic immune-inflammation index and coagulation parameters for hospital-acquired pneumonia in patients with traumatic brain injury.American journal of translational research · 2026Article
- Clinical outcomes in hospitalized patients with community-acquired pneumonia: A comprehensive analysis of associated factors.PloS one · 2026Article
- Systemic inflammatory indices and 28-day mortality in severe pneumonia: a retrospective single-center exploratory study.Frontiers in medicine · 2026Article
- Systemic immune-inflammation index combined with blood urea nitrogen to albumin ratio predicts 28-day mortality in sepsis: a retrospective cohort study.Frontiers in physiology · 2026Article
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Abstract
Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality worldwide, underscoring the need for accessible and cost-effective biomarkers to support early risk assessment. This retrospective study investigated the prognostic performance of two systemic inflammatory indices-the Systemic Immune-Inflammation Index (SII) and the Systemic Inflammation Response Index (SIRI)-in 240 adults hospitalized with CAP between January and December 2024. The primary outcome was 30-day all-cause mortality. Logistic regression and receiver operating characteristic (ROC) analyses were applied to compare these indices with established severity scores, CURB-65 and the Pneumonia Severity Index (PSI). Thirty-day mortality occurred in 15.4% of patients. Non-survivors exhibited significantly higher SII values (
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