Evidence map›Paper›PMID 41471799›Full record

ReviewMolecules (Basel, Switzerland)2025

Wheat as a Storehouse of Natural Antimicrobial Compounds.

Eva Scarcelli, Domenico Iacopetta, Jessica Ceramella, Daniela Bonofiglio, Alessia Catalano, Giovanna Basile, Francesca Aiello, Maria Stefania Sinicropi

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eva ScarcelliDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0009-0004-5303-4148
Domenico IacopettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0000-0001-5179-7118
Jessica CeramellaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0000-0002-1386-3601
Daniela BonofiglioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0000-0002-4142-0496
Alessia CatalanoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", Via Orabona, 4, 70126 Bari, Italy.ORCID 0000-0002-7420-4706
Giovanna BasileDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.
Francesca AielloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0000-0001-6846-5582
Maria Stefania SinicropiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata Di Rende, Italy.ORCID 0000-0003-2435-8931

Funding

"Patti Territoriali per l'Alta formazione per le imprese", art. 14-bis, comma 2, D.L. n. 152/2021 H22C24000120001PR CALABRIA FESR FSE 2021 - 2027. Valorizzazione dei grani antichi calabresi per la tutela della salute e dell'ambiente - GrAnCala' (Grani Antichi Calabria) J19I24002180005
6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) represents a global health challenge, contributing to elevated rates of morbidity and mortality. This growing problem is attributed to the widespread and indiscriminate use of antimicrobial agents. In response, current research is focused on identifying novel strategies to combat AMR, with particular attention to alternative therapeutic agents. Natural antimicrobials have emerged as promising candidates. Among these, wheat, one of the most cultivated food crops in the world, is identified as a valuable source of such bioactive compounds. Beyond its nutritional importance and prevalent use in food production, wheat is rich in polyphenols, small peptides, benzoxazinoids, 1,4-benzoquinones, and 5-

methodsTwo databases, i.e., Google Scholar and Scopus, were screened using different keywords.

resultsA series of key compounds responsible for these effects were identified, evaluating wheat's potential role as a sustainable source of novel and potent antimicrobial agents.

conclusionsThis review aims to collect the latest findings regarding the antimicrobial potential of different wheat varieties and their by-products.

Indexed as

Anti-Infective AgentsEdible GrainPhytochemicalsTriticumBacteriaDrug Resistance, MicrobialFood Loss and WasteFungiAnti-Infective AgentsFood Loss and WastePhytochemicalsantimicrobial peptidesnatural antimicrobialspolyphenolswheatwheat by-products

Identifiers

PMID41471799
PMCPMC12736179

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.