Identification, Molecular Docking Mechanism and Cellular Activity of Selenium-Enriched ACE Inhibitory Peptides from Oysters.

Zhuangzhuang Yue, Zhen Xia, Fei Xu, Bingbing Chen, Shufei Jiao, Xingtang Liang, Yanzhen Yin, Jianyin Miao

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhuangzhuang YueGuangxi Key Laboratory of Green Chemical Materials and Safety Technology, School of Petroleum and Chemical Engineering, Beibu Gulf University, Qinzhou 535011, China.

Zhen XiaGuangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou 510642, China.

Fei XuGuangxi Key Laboratory of Green Chemical Materials and Safety Technology, School of Petroleum and Chemical Engineering, Beibu Gulf University, Qinzhou 535011, China.

Bingbing ChenGuangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou 510642, China.

Shufei JiaoGuangxi Key Laboratory of Green Chemical Materials and Safety Technology, School of Petroleum and Chemical Engineering, Beibu Gulf University, Qinzhou 535011, China.

Xingtang LiangGuangxi Key Laboratory of Green Chemical Materials and Safety Technology, School of Petroleum and Chemical Engineering, Beibu Gulf University, Qinzhou 535011, China.

Yanzhen YinGuangxi Key Laboratory of Green Chemical Materials and Safety Technology, School of Petroleum and Chemical Engineering, Beibu Gulf University, Qinzhou 535011, China.

Jianyin MiaoGuangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou 510642, China.

Funding

the Guangxi Key Research and Development Plan AB21220065

6 · The paper itself

Abstract

Selenium-enriched oyster proteins were hydrolyzed using trypsin to obtain peptides with angiotensin-I-converting enzyme (ACE) inhibitory activity. The hydrolysate was purified by ultrafiltration and two-step reversed-phase high-performance liquid chromatography (RP-HPLC), yielding the most active fraction M4-2 (selenium content: 37.00 ± 0.56 mg/kg; IC

Indexed as

Angiotensin-Converting Enzyme InhibitorsMolecular Docking SimulationOstreidaePeptidesPeptidyl-Dipeptidase ASeleniumAmino Acid SequenceAnimalsCell LineHumansAngiotensin-Converting Enzyme InhibitorsPeptidesPeptidyl-Dipeptidase ASeleniumantihypertensive activitymolecular dockingoyster proteinSe-enriched ACE inhibitory peptides

Identifiers

PMID41471840

DOI10.3390/molecules30244818

PMCPMC12735907

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.