Evidence map›Paper›PMID 41471843›Full record

ArticleMolecules (Basel, Switzerland)2025

The Iodine-Dextrin-Lithium Complex: Morphology, Antibacterial Activity, and Cytotoxicity.

Daniil Shepilov, Seitzhan Turganbay, Ardak Jumagaziyeva, Tamara Bukeyeva, Dana Askarova, Didar Bolatova, Yerlan Doszhanov, Arman Zhumazhanov, Almagul Kerimkulova, Karina Saurykova and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniil ShepilovJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Kazakhstan.ORCID 0009-0003-0471-0587
Seitzhan TurganbayJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Kazakhstan.ORCID 0000-0001-9621-3534
Ardak JumagaziyevaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Kazakhstan.ORCID 0000-0002-8610-7321
Tamara BukeyevaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Kazakhstan.ORCID 0000-0002-3100-6523
Dana AskarovaJSC Scientific Center for Anti-Infectious Drugs, Almaty 050060, Kazakhstan.
Didar BolatovaDepartement of Science, International IT University, Almaty 050040, Kazakhstan.
Yerlan DoszhanovUNESCO Chair in Sustainable Development, Al-Farabi Kazakh National University, Al-Farabi Ave., 71, Almaty 050040, Kazakhstan.ORCID 0000-0002-3454-8889
Arman ZhumazhanovUNESCO Chair in Sustainable Development, Al-Farabi Kazakh National University, Al-Farabi Ave., 71, Almaty 050040, Kazakhstan.ORCID 0009-0004-6256-9814
Almagul KerimkulovaDepartment of Material Sciences, Nanotechnology and Engineering Physics, Satbayev University, Satbayev Str. 22a, Almaty 050013, Kazakhstan.ORCID 0000-0001-8048-4970
Karina SaurykovaInstitute of Combustion Problems, Almaty 050012, Kazakhstan.
Aitugan SabitovInstitute of Combustion Problems, Almaty 050012, Kazakhstan.ORCID 0000-0003-3677-8685

Funding

Ministry of Science and Higher Education of the Republic of Kazakhstan №BR24992760 and №AP19576946
6 · The paper itself

Abstract

A new iodine-dextrin-lithium complex (IDLC) was synthesized and structurally characterized as a hybrid supramolecular system combining antiseptic, stabilizing, and biocompatible components. The compound integrates iodine as the primary antimicrobial agent, lithium as a coordination and stabilization element, and dextrin as a biodegradable polysaccharide matrix enabling sustained release. Physicochemical analyses confirmed the formation of a uniform, thermally stable complex. Biological evaluation revealed strong bactericidal activity, with minimum bactericidal concentrations (MBCs) ranging from 1.95 to 15.63 µg mL

Indexed as

Anti-Bacterial AgentsCoordination ComplexesDextrinsIodineLithiumAnimalsAntineoplastic AgentsCell Line, TumorCell SurvivalDogsHumansMadin Darby Canine Kidney CellsMicrobial Sensitivity TestsAnti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesDextrinsIodineLithiumantimicrobial activitycytotoxicitydextriniodinepolymer–iodine complex

Identifiers

PMID41471843
PMCPMC12736063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.