Evidence map›Paper›PMID 41472136›Full record

ReviewVeterinary sciences2025

A Comprehensive View on the Mechanisms of Coronavirus Escaping Innate Immunity.

Yichen Liu, Hao Lu, Jinyuan Li, Yuqing Xie, Gaowei Hu, Shengmei Pang, Siqi Lian, Jiaqi Liu, Guoqiang Zhu, Xueyan Ding

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yichen LiuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Hao LuMolecular Biology Laboratory, Zhengzhou Normal University, Zhengzhou 450044, China.ORCID 0009-0005-3000-1893
Jinyuan LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Yuqing XieCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0009-0004-1560-7371
Gaowei HuCollege of Life Sciences, Taizhou University, Taizhou 318000, China.
Shengmei PangCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Siqi LianCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jiaqi LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Guoqiang ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Xueyan DingCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-1238-0621

Funding

Henan Postdoctoral Research Foundation HN2024113National Natural Science Foundation of China 32503083Science and Technology Plan Project of Taizhou 22nya08
6 · The paper itself

Abstract

Coronaviruses are a group of widespread infectious pathogens that pose a serious threat to human and animal health. Corona Virus Disease 2019, instigated by severe acute respiratory SARS-CoV-2, has presented an unprecedented challenge to global public health in recent years. The host innate immune system is the first line of defense against pathogens, which plays a key role in inhibiting the initial infection of viruses and regulating the initiation and development of acquired immunity. However, coronaviruses can suppress the host's innate immune response through their unique immune escape mechanisms, which is one of the key strategies for coronavirus pathogenesis. This review focuses on the host's innate immune sensors, innate antiviral immune responses, and the mechanisms employed by coronaviruses to evade and suppress the innate immune system. And we hope that it will contribute to a comprehensive understanding of the escape mechanism of coronaviruses regarding innate immunity and the pathogenesis of coronaviruses.

Indexed as

antiviral mechanismscoronavirusesimmune escape mechanismsinnate immunity

Identifiers

PMID41472136
PMCPMC12737352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.