ArticleJournal of cosmetic dermatology2026
Effects of Autologous Blood-Derived Extracellular Vesicles on Skin Regeneration and Anti-Aging: A Clinical Study.
Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Effects of Autologous Blood-Derived Extracellular Vesicles on Skin Regeneration and Anti-Aging: A Clinical Study.Journal of cosmetic dermatology · 2026Article
- Efficacy of Exosome-Based Therapies for Skin Rejuvenation: A Systematic Review of Human Studies.Cureus · 2026Review
- Effects of Autologous Blood-Derived Extracellular Vesicles on Skin Regeneration and Anti-Aging: A Clinical Study.Journal of cosmetic dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAutologous blood-derived extracellular vesicles (EVs) have gained attention as a novel therapeutic approach for skin rejuvenation. This study evaluates their efficacy in improving wrinkles, lifting, hydration, barrier function, tone, radiance, texture, and pore size in human subjects.
aimThis study aimed to evaluate the clinical efficacy of a single intradermal injection of autologous blood-derived EVs in improving multiple skin parameters, including wrinkle reduction, skin lifting, hydration, barrier function, tone, radiance, texture, and pore size, over a three-week period.
methodsTwenty-five participants aged 40-59 underwent a single facial injection of autologous blood-derived EVs. Evaluations were conducted before treatment, 5 days post-treatment, and 3 weeks post-treatment using objective skin analysis tools and subjective self-assessment questionnaires.
resultsStatistically significant improvements (p < 0.05) were observed in wrinkle depth, skin lifting, hydration, elasticity, and barrier function at both 5-day and 3-week time points. Skin tone, radiance, texture, and pore size also improved significantly over the study period. Subjective self-assessments corroborated the instrumental findings, with a marked increase in participant-reported satisfaction. No adverse reactions or safety concerns were reported during the study.
conclusionsThis study demonstrates the clinical efficacy and safety of autologous blood-derived EVs in facial rejuvenation, supporting their potential as a non-invasive cosmetic treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.