Evidence map›Paper›PMID 41472491›Full record

ArticleInternal medicine journal2026

Physical multimorbidity and quit outcomes in a publicly funded smoking cessation programme.

Polina Kyrychenko, Benjamin K C Wong, Scott Veldhuizen, Nadia Minian, Laurie Zawertailo, Peter Selby, Osnat C Melamed

Abstract read
In one paragraph

Article in Internal medicine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Author reply.Internal medicine journal · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Polina KyrychenkoTemerty Faculty of Medicine, University of Toronto, Toronto, Ontatio, Canada.ORCID 0000-0001-8271-379X
Benjamin K C WongINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Scott VeldhuizenINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Nadia MinianINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Laurie ZawertailoINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Peter SelbyINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.ORCID 0000-0001-5401-2996
Osnat C MelamedINTREPID Lab, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.ORCID 0000-0002-9663-2226

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the association between physical multimorbidity and 6-month quit outcomes among treatment-seeking smokers.

methodsWe analysed data from 120 732 adults enrolled in Ontario's largest publicly funded smoking cessation programme. At enrolment, participants self-reported zero, one or two or more chronic physical health conditions. The primary outcome was 7-day point prevalence abstinence at 6 months. We used mixed-effects logistic regression to assess the association between multimorbidity and quit outcomes, adjusting for demographic and tobacco use characteristics.

resultsOf participants, 39.4% reported no conditions, 26.8% reported one and 33.8% reported two or more. Those with multimorbidity were older, had lower socioeconomic status and showed higher tobacco dependence but also greater motivation to quit. Compared to individuals without comorbidities, those with one condition (OR = 0.94, 95% CI: 0.90-0.98) and those with two or more (OR = 0.81, 95% CI: 0.77-0.85) had lower odds of quitting. Mental health conditions further reduced quit success among those with physical multimorbidity. DISCUSSION: Physical multimorbidity is associated with 19% lower odds of cessation success despite high motivation to quit. Tailored, intensive cessation support may improve outcomes for this high-risk group.

Indexed as

MultimorbiditySmoking CessationTobacco Use DisorderAdultAgedFemaleHumansMaleMiddle AgedMotivationOntarioSmokingTreatment Outcomechronic medical conditionsmultimorbiditysmoking cessationtobacco use

Identifiers

PMID41472491
PMCPMC12978208

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.