ArticleAmerican journal of preventive cardiology2025
Ectopic Fat distribution and adverse muscle composition in South Asians: Findings from the UK biobank.
Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Greater Glycaemic Responses to Bodyweight Change in South Asians Than White Europeans at High Risk of Type 2 Diabetes.Diabetes, obesity & metabolism · 2026Trial
- Muscle in fat trouble: The rise of IMAT in metabolic and musculoskeletal disease.Molecular metabolism · 2026Review
- Lean, Non-Autoimmune Young-Onset Diabetes in Bangladesh: A Metabolically Obese Phenotype With Disproportionate Insulin Secretory Defect.Endocrinology, diabetes & metabolism · 2026Article
- Article
- Cardiovascular-kidney-metabolic syndrome in Indonesia: a commentary on the need for integrated management and policy action.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Background: South Asians (SA) have higher risk of cardiometabolic disease compared to other ethnicities. However, detailed analyses of body compositional profile (BCP) in large cohorts with inclusion of ectopic fat depots and muscle composition is lacking. Methods: Using MRI data from UK biobank, we compared body compositional data in South Asians ( Results: SAs had higher overall levels of fat compared to EUR (mean difference in: visceral adipose tissue 0·20 L; subcutaneous adipose tissue 0·93 L; liver fat 0·92 pp; muscle fat infiltration (MFI) 0·59 pp, all Conclusion: SAs have greater visceral, liver, and muscle fat accumulation, but lower muscle volume compared to EUR. These findings may underlie their greater risk for T2D and atherothrombotic outcomes. Lifestyle changes to prevent or reduce weight gain can help offset cardiometabolic risks in SAs by facilitating favorable changes in body composition.
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Registered trials
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