Evidence map›Paper›PMID 41473018›Full record

ArticleAmerican journal of preventive cardiology2025

Wearable device-measured physical activity and risk of MAFLD in adolescents.

Ruli Wang, Congwei You, Zijuan Dong, Qingqing Zheng, Xiaowei Zheng, Liangbin Zhou, Xiaolei Wang, Le Zhang, Haoyang Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ruli WangDepartment of Paediatrics, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, China.
Congwei YouDepartment of Paediatrics, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Zijuan DongDepartment of Paediatrics, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, China.
Qingqing ZhengDepartment of Paediatrics, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Xiaowei ZhengPublic Health Research Center and Department of Public Health and Preventive Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi, China.
Liangbin ZhouDepartment of Biomedical Engineering, Faculty of Engineering, The Chinese University of Hong Kong, Hong Kong, China.
Xiaolei WangDepartment of Paediatrics, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Le ZhangDepartment of Paediatrics, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, China.
Haoyang ZhangDepartment of Experimental Medical Science, Lund University, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While physical activity is known to affect the risk of MAFLD in adults, evidence in adolescents is limited and often based on self-reported questionnaires. We therefore used wearable device-based measurements to investigate the association between physical activity and MAFLD in adolescents. Methods: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) database for adolescents aged 12-19 years during the 2003-2006 and 2011-2014 cycle. Physical activity was measured using wearable accelerometers, averaged across all valid wearing days. Weighted multivariate logistic regressions were applied to assess associations between physical activity (overall, daytime, and nighttime) and MAFLD. Result: Among 5705 adolescents, higher physical activity levels were strongly associated with lower odds of MAFLD in the 2003-2006 cycle, with a clear dose-response trend across quartiles ( Conclusion: Our results suggest that higher levels of physical activity, especially during the daytime, may protect against MAFLD in adolescents. Our findings offer partial evidence for the role of circadian activity patterns in MAFLD risk and underscore the need for future studies to validate these associations.

Indexed as

AdolescentMAFLDPhysical activityWearable devices

Identifiers

PMID41473018
PMCPMC12746288

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.