ArticleFrontiers in endocrinology2025
Enhancing insulin secretion by pancreatic β-cell redifferentiation: a study of the anti-diabetic effects of berberine
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The β-cell dedifferentiation and impaired glucose-stimulated insulin secretion (GSIS) contribute to the pathogenesis of diabetes. Berberine (BBR), a natural compound with known anti-diabetic therapeutic properties, has been investigated for its potential role in preserving β-cell function. This study aims to elucidate the molecular mechanism by which BBR prevents β-cell dedifferentiation and restores deteriorated GSIS. In this
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