Fulminant disseminated human parvovirus B19 infection: Case report.

Yan Chen, Wei Jiang, Li Weng

Abstract read

In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yan ChenMedical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.

Wei JiangMedical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.

Li WengMedical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fulminant, disseminated Human parvovirus B19 (HPV B19) infection is uncommon and can be fatal if unrecognized. Case presentation: A 35-year-old man developed abrupt confusion on the second day of incarceration. He was admitted to intensive care with acute kidney, liver injury, coagulopathy, thrombocytopenia, and persistent hematochezia. The etiology remained unclear until next-generation sequencing detected HPV B19 DNA in blood, cerebrospinal fluid (CSF), bronchoalveolar lavage fluid, and ascitic fluid. On illness Day 32, B19 infection was confirmed by quantitative PCR from blood, CSF, and a rectal biopsy. Despite negative B19-specific IgM, the patient improved after four weeks of supportive care and two courses of intravenous immunoglobulin, with recovery of renal, hepatic, and respiratory function and resolution of rectal lesions. Conclusions: Disseminated HPV B19 infection should be considered in unexplained multiorgan dysfunction, even in the absence of rash or IgM seroconversion. Early PCR-based testing of blood and affected tissues can be diagnostic.

Indexed as

Case reportDisseminated infectionMultiorgan failureParvovirus B19

Identifiers

PMID41473479

DOI10.1016/j.idcr.2025.e02445

PMCPMC12747243

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.