ArticleAnnals of African medicine2026
Role of Automated Red Cell Exchange in Sickle Cell Anemia and Poisoning.
Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractRed cell exchange (RCE) is the removal of a patient's diseased red cells and replacing them with normal donor red cells either manually or using an automated cell separator. It is the treatment of choice in patients with sickle cell disease (SCD) presenting with acute stroke and severe acute chest syndrome with hypoxia. However, its use is limited because of the need for sophisticated equipment, specialized staff, and high cost of procedure. A total of 10 automated red blood cell exchanges were performed from January 2016 to December 2023 in patients who were in the age group 2 year-35 year with mean age 18.6 years. All the procedures were performed on Com.Tec (version 04.03.07) which has inbuilt software program. Among these 10 patients, 7 were male and 3 were female patients. Out of 10 patients, 9 were of SCD and one was of poisoning. In our study, 1 out of 10 patients had alloantibody Anti E, so antigen negative, phenotype matched, crossmatch compatible blood was given. The targeted and final fraction of red cell remaining (FCR) values were kept at <30% which was achieved in all cases. RCE is a safe and effective therapeutic treatment procedure with minimal or no side effects when performed at the right time by trained staff.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.