Trial reportBMC psychiatry2025
Computer-assisted cognitive remediation (CACR) as a recovery-oriented intervention for schizophrenia: a randomized controlled trial.
Trial report in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecovery-oriented care focuses on empowering individuals with schizophrenia to live meaningful lives despite persistent challenges. Schizophrenia often involves cognitive impairments and reduced participation in purposeful activities, contributing to poor psychosocial outcomes. Although computer-assisted cognitive remediation (CACR) is a well-established method for improving cognitive function, its potential to enhance recovery-related outcomes remains underexplored.
objectivesThis study investigated the impact of CACR on personal recovery, psychological needs satisfaction, self-esteem, and occupational engagement in individuals with schizophrenia.
methodsIn a double-blind randomized controlled trial, 54 outpatients with schizophrenia were allocated to either CACR (n = 27) or an active control condition (n = 27). The CACR group completed 30 sessions of computerized cognitive training using four CANTAB tasks (visual attention, memory, and planning) under therapist supervision, incorporating feedback and meta-cognitive reflection. The control group participated in matched sessions of computerized leisure activities without cognitive training or therapist guidance. Outcomes included the Recovery Assessment Scale–Domains and Stages (RAS-DS), Engagement in Meaningful Activities Survey (EMAS), Basic Psychological Needs Satisfaction in General Scale (BPNSG-S), Rosenberg Self-Esteem Scale (RSES), and General Health Questionnaire-12 (GHQ-12), assessed at baseline, post-intervention, and 3-month follow-up.
resultsCACR group experienced significant improvements in personal recovery, autonomy, competence, self-esteem, and engagement in meaningful activities (all p < 0.05). Psychological well-being also improved at follow-up. However, no significant changes were observed in relatedness. The control group demonstrated only transient or non-significant fluctuations across outcomes.
conclusionsThese findings suggest that CACR can support key elements of recovery, offering a person-centered intervention beyond cognitive improvement. CACR may serve as a valuable adjunct to standard care in schizophrenia by promoting recovery-oriented outcomes such as autonomy, self-esteem, and meaningful activity engagement. However, the findings should be interpreted with caution given the relatively small sample size and short follow-up period. Future studies with larger and more diverse samples, and longer observation, are needed to confirm and extend these results. CLINICAL TRIAL NUMBER: The study was registered with www.irct.ir : IRCT20180317039116N2, on 2023/01/28. Prospectively registered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.