Evidence mapPaperPMID 41476282Full record

ReviewDiscover oncology2025

The role of microRNAs on autophagy in cervical cancer: review.

Mulu Shiferw Asfaw, Woldeteklehaymanot Kassahun

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mulu Shiferw AsfawDepartment of Biomedical Sciences, College of Health Sciences, Woldia University, PoBox: 400, Woldia, Ethiopia. mulushi9804@gmail.com.
Woldeteklehaymanot KassahunDepartment of Medical Laboratory Science, College of Health Sciences, Woldia University, Woldia, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is one of the top five most common cancers among women worldwide. A key cellular alteration in CC is the dysregulation of autophagy a vital process for maintaining cell homeostasis by degrading and recycling damaged components via lysosomes. Disrupted autophagy is associated with various stages of cancer development. This review explores the role of microRNAs (miRNAs) in regulating autophagy in cervical cancer. miRNAs influence autophagy by targeting specific genes or signaling pathways, acting either as promoters or suppressors of the process. Many microRNAs (miRNAs) involved in autophagy are dysregulated in cervical cancer. For example, miR-203, miR-34a, miR-23b, miR-100, and miR-145, known to activate autophagic proteins in various diseases, are found to be suppressed in cervical cancer. This highlights the significant potential of miRNAs in regulating autophagy, making them valuable as diagnostic and prognostic markers, as well as therapeutic targets.

Indexed as

AutophagyCervical cancermiRNA

Identifiers

PMID41476282
PMCPMC12864638

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.