Evidence map›Paper›PMID 41476369›Full record

ArticlePlant communications2026

Pyramiding elite alleles of the genetically linked OsNRAMP5 and OsHMA3 confers low Cd accumulation in rice grains without compromising stress tolerance.

Li Tang, Jiao Wang, Zhongying Ji, Xingrong Li, Xiaoshuang Liu, Qiming Lv, Pengcheng Wei, Xianlan Hu, Yaokui Li, Bigang Mao and 6 more

Abstract read
In one paragraph

Article in Plant communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. From paddy soil to dining table: biological biofortification of rice with zinc.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Li TangState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Longping Agricultural College, Hunan University, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China. Electronic address: tangli@hhrrc.ac.cn.
Jiao WangLongping Agricultural College, Hunan University, Changsha 410125, China.
Zhongying JiLongping Agricultural College, Hunan University, Changsha 410125, China.
Xingrong LiLongping Agricultural College, Hunan University, Changsha 410125, China.
Xiaoshuang LiuCollege of Agronomy, Anhui Agricultural University, Hefei 230036, China.
Qiming LvState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Longping Agricultural College, Hunan University, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Pengcheng WeiCollege of Agronomy, Anhui Agricultural University, Hefei 230036, China.
Xianlan HuLongping Agricultural College, Hunan University, Changsha 410125, China.
Yaokui LiState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Bigang MaoState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Longping Agricultural College, Hunan University, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Ye ShaoState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Yan PengState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Zhongwei WeiState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China.
Lianyang BaiState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Longping Agricultural College, Hunan University, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China. Electronic address: lybai@hunaas.cn.
Caiyan ChenInstitute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China. Electronic address: cychen@isa.ac.cn.
Bingran ZhaoState Key Laboratory of Hybrid Rice, Hunan Hybrid Rice Research Center, Hunan Academy of Agricultural Sciences, Changsha 410125, China; Longping Agricultural College, Hunan University, Changsha 410125, China; Yuelushan Laboratory, Changsha 410128, China. Electronic address: brzhaorice@163.com.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Excessive cadmium (Cd) accumulation in rice grains poses a serious threat to food security. Cd uptake by roots and its subsequent transport to grains are mediated by mineral element transporters in rice. Consequently, efforts to reduce Cd accumulation are often accompanied by unintended decreases in essential mineral elements. Achieving a substantial reduction in grain Cd concentrations while maintaining appropriate levels of mineral elements therefore remains a major bottleneck in low-Cd rice breeding. Here, we report that pyramiding elite alleles of OsNRAMP5 and OsHMA3, two key genes encoding Cd transporters, confers low Cd accumulation in grains without inducing sensitivity to manganese (Mn) deficiency in Layandabu (LAA), a tropical japonica rice cultivar. A serine-to-phenylalanine substitution at position 313 in OsNRAMP5

Indexed as

CadmiumCation Transport ProteinsOryzaPlant ProteinsAllelesEdible GrainManganeseStress, PhysiologicalCadmiumCation Transport ProteinsManganesePlant Proteinsallelic variationgrain cadmiumintracellular traffickingmanganese uptakeNRAMPVAMP-associated protein

Identifiers

PMID41476369
PMCPMC13084080

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.