Evidence map›Paper›PMID 41476853›Full record

ArticleInternational journal of dentistry2025

Comparative Evaluation of Locally Applied Chlorhexidine 1% Gel and

Ishika Sarkar, Pritish Chandra Pal, Swet Nisha, Debika Karmakar, S R Savan, Dhanraj Budhai

Abstract read
In one paragraph

Article in International journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ishika SarkarDepartment of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India, icare-haldia.org.ORCID https://orcid.org/0009-0003-5555-4000
Pritish Chandra PalDepartment of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India, icare-haldia.org.ORCID https://orcid.org/0000-0002-7654-7649
Swet NishaDepartment of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India, icare-haldia.org.ORCID https://orcid.org/0000-0003-2873-5861
Debika KarmakarDepartment of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India, icare-haldia.org.ORCID https://orcid.org/0009-0004-4278-3530
S R SavanDepartment of Periodontology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India, icare-haldia.org.
Dhanraj BudhaiDepartment of Periodontology, University of Guyana School of Dentistry, Georgetown, Guyana.ORCID https://orcid.org/0009-0003-5648-0138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontal disease is polymicrobial in nature and to control the infection we need to target the inflammatory component. Nonsurgical periodontal therapy is used for mechanical debridement. Use of agents along with nonsurgical periodontal therapy is gaining momentum. Locally delivered agents like antibiotics and herbal products are used in nonsurgical and surgical periodontal therapy. Phytotherapy offers antioxidant, antimicrobial action and has less chances of drug resistance. Objective: This study design compared locally delivered chlorhexidine (CHX) 1% gel and Material and Method: Forty-six subjects diagnosed with Grade II/III localized periodontitis were randomly assigned into two groups. After thorough SRP, CSPE gel placement was done in the test group and 1% CHX gel in the control group. Clinical parameters measured were probing pocket depth (PPD), clinical attachment level (CAL) and microbiological analysis (bacterial culture from pocket sample) was done prior to SRP and at 60 days. Results: Both the 1% CHX and CSPE gel provide comparable outcome ( Conclusion: Locally delivered herbal CSPE gel can be an effective, economical,and antibacterial gel as an adjunctive treatment of periodontitis.

Indexed as

antimicrobialantioxidantchlorhexidineCitrus sinensiscontrolled release drugslocal drug deliveryperiodontitis

Identifiers

PMID41476853
PMCPMC12752897

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.