Evidence map›Paper›PMID 41476994›Full record

ArticleInternational journal of endocrinology2025

Exploratory Research on the Urine Proteome in Patients With Diabetic Peripheral Neuropathy.

Lilong Wei, Yongwei Jiang, Haitong Wang, Jianqiang Wu, Chengwu Han, Yuliang Zhan, Yun Zhou, Yongtong Cao, Youhe Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lilong WeiClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.ORCID https://orcid.org/0009-0001-6753-0167
Yongwei JiangClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.ORCID https://orcid.org/0000-0002-4974-0283
Haitong WangGene Engineering Drug and Biotechnology Beijing Key Laboratory, College of Life Sciences, Beijing Normal University, Beijing, 100871, China, bnu.edu.cn.ORCID https://orcid.org/0009-0001-3216-4726
Jianqiang WuInstitute of Clinical Medicine, National Infrastructure for Translational Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730, China, cams.ac.cn.ORCID https://orcid.org/0000-0001-6773-9289
Chengwu HanClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.
Yuliang ZhanClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.ORCID https://orcid.org/0009-0008-2126-7130
Yun ZhouClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.ORCID https://orcid.org/0000-0002-0600-9511
Yongtong CaoClinical Laboratory, China-Japan Friendship Hospital, Beijing, 100029, China, zryhyy.com.cn.ORCID https://orcid.org/0000-0002-2019-7088
Youhe GaoGene Engineering Drug and Biotechnology Beijing Key Laboratory, College of Life Sciences, Beijing Normal University, Beijing, 100871, China, bnu.edu.cn.ORCID https://orcid.org/0000-0001-7159-2558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes and there are currently no biomarkers for DPN in clinical practice. The objective of this study was to explore the diagnostic value of urine for diseases and discover potential markers. Urinary proteomics was used to analyze urine samples from patients with DPN and healthy individuals. Quantitative analysis of mass spectrometry data was performed using both group-based and paired individual analysis strategies. A total of 2611 proteins were identified, of which 1759 were quantifiable, and 312 proteins showed significant differences (fold change > 2, adjusted

Indexed as

diabetesdisease biomarkersneuropathyperipheral nerve injuryurinary proteomics

Identifiers

PMID41476994
PMCPMC12752815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.