Evidence map›Paper›PMID 41477335›Full record

ArticleActa pharmaceutica Sinica. B2025

IGF2BP1 positively regulates CircOGDH accumulation in hypoxia induced stress granules.

Xuanlin Su, Jiankun Zang, Yaping Wang, Shiqing Zhang, Panwen Wu, Wei Chen, Lei Shi, Yousheng Wu, Die Deng, Kaiwei Cai and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xuanlin SuDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Jiankun ZangDepartment of Neurology, The First People's Hospital of Foshan, Foshan 528000, China.
Yaping WangDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Shiqing ZhangState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou 510630, China.
Panwen WuDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Wei ChenDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Lei ShiState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou 510630, China.
Yousheng WuDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Die DengDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Kaiwei CaiDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Hongcheng MaiDepartment of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Anding XuDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Dan LuDepartment of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ischemic penumbra is critical in acute ischemic stroke (AIS) treatment, yet the regulation of precise RNA modification pathways remains unclear. Using a mouse model of ischemic stroke and human postmortem brain samples, we demonstrate that

Indexed as

Acute ischemic strokeCircRNAIGF2BP1Ischemic penumbram6A readerN6-MethyladenosineStress granulesTherapeutic target

Identifiers

PMID41477335
PMCPMC12750160

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.