Evidence map›Paper›PMID 41478941›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Platforms to Evaluate Flavivirus-Induced Immunoinflammatory Responses and Their Pathogenesis.

Viviane L Batista, Jennifer R Martins, Danielle Cunha Teixeira, Jéssica A B Pereira, Victor R M Costa, Felipe Rocha da Silva Santos, Angélica Samer Lallo Dias, Mauro Martins Teixeira, Celso Martins Queiroz-Junior, Vivian V Costa

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Viviane L Batista *Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Jennifer R Martins *Grupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Danielle Cunha TeixeiraGrupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Jéssica A B PereiraDepartamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Victor R M CostaDepartamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Felipe Rocha da Silva SantosGrupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Angélica Samer Lallo DiasGrupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Mauro Martins TeixeiraDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Celso Martins Queiroz-JuniorGrupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Vivian V CostaGrupo de Pesquisa em Arboviroses, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. vivianvcosta@ufmg.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquito-borne diseases induced by viruses belonging to the Flavivirus genus such as Dengue, Zika, and Yellow fever have proven to cause widespread outbreaks over time. These viruses are prevalent mainly in tropical and subtropical regions and it is estimated that more than 100 countries are affected by one or more of these pathogens. The diseases may have mild clinical manifestations in common, such as fever, joint pain, headaches, and diarrhea; however, they can progress to serious reactions and, sometimes, trigger significant neurological malformations and post-infection sequelae, as in infection with Zika virus. To better understand their pathogenicity and tackle pharmacological development, animal and cell culture models have been developed. In the current chapter, we present in vivo platforms to study flavivirus-induced diseases, which allow us to mimic human infection to investigate clinical parameters, inflammatory, and viral mechanisms.

Indexed as

FlavivirusFlavivirus InfectionsInflammationAnimalsDisease Models, AnimalHumansMiceZika VirusDengueFlavivirusYellow feverZika

Identifiers

PMID41478941

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.