Evidence map›Paper›PMID 41479114›Full record

ReviewExperientia supplementum (2012)2026

Exploring the Role of Long Noncoding RNAs (lncRNAs) as Biomarkers in Cancers.

Shahid Bashir, Mohammad Uzair

Abstract readReview
PubMed Publisher
In one paragraph

Review in Experientia supplementum (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shahid BashirNeuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.
Mohammad UzairDepartment of Bioengineering, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The whole human genome sequence analysis has identified a large proportion of transcripts that lack protein-encoding function known as noncoding RNAs (ncRNAs). Long ncRNAs (lncRNAs) are transcripts consisting of more than 200 nucleotides. LncRNAs are identified as key regulators for diverse biological processes, including gene expressions, epigenetic modulations, transcriptional and translational regulation. LncRNAs-based mechanisms control gene activation, and cellular processes, while the dysregulated lncRNAs are associated with various disorders, including cancer. Moreover, lncRNAs have potential in diagnosis and prognosis of cancer. Several lncRNAs contribute to cancer development, metastatic cascade, and their molecular regulations in cancer development. The aberrant expression of lncRNAs regulates tumorigenesis, proliferation, metastasis, cancer stage, tumor size, and overall survival rates. Several lncRNAs are highly expressed or downregulated in several human tumors, behaving as oncogenes or tumor suppressors, respectively. The unique expression level of oncogenic lncRNAs provides a possibility to utilize them as a promising predictive biomarker of cancer.

Indexed as

Biomarkers, TumorNeoplasmsRNA, Long NoncodingEpigenesis, GeneticGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorRNA, Long NoncodingBiomarkersMetastasisOncogenic lncRNAsTherapeutic targetsTumor-suppressor lncRNAs

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.