ReviewFrontiers in veterinary science2025
The pig as a medical model for gynecological diseases: an applied perspective.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Glycation-Driven Mitochondrial and ER Stress Underlies Iodoacetic Acid-Induced Apoptosis in Porcine Uterus and Oviduct Epithelial Cells.Antioxidants (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gynecological diseases pose substantial risks to female reproductive health and overall wellbeing. To improve disease prevention and treatment, researchers continue to develop experimental models that faithfully replicate key features of the female reproductive system. Porcine models have gained increasing attention in gynecological research due to their substantial similarities to humans in anatomical structure, physiological function, and pathological processes. This review aims to evaluate the practical applications of porcine models for investigating gynecological disorders. We examine the use of porcine models in studying common gynecological diseases such as endometritis, infertility, and ovarian cancer, analyze their advantages and limitations, and discuss their role in genetic engineering applications. Notably, porcine models have facilitated key advances in gynecological research, including elucidating neuropeptide-mediated uterine dysmotility in endometritis, refining surgical techniques for uterine transplantation and vaginoplasty in infertility management, and evaluating dihydroartemisinin as a potential therapeutic agent for ovarian cancer. This analysis aims to characterize the distinctive features of porcine models for gynecological research, thereby facilitating the selection of optimal animal models for future preclinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.