Evidence map›Paper›PMID 41479582›Full record

ArticleWorld journal of virology2025

Adherence to antiviral treatment among people living with chronic hepatitis B: A global survey.

Suzanne J Block, Yasmin Ibrahim, Chari Cohen

Abstract read
In one paragraph

Article in World journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Suzanne J BlockDepartment of Health, Behavior and Society Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States. sblock8@jhmi.edu.
Yasmin IbrahimHepatitis B Foundation, Doylestown, PA 18902, United States.
Chari CohenHepatitis B Foundation, Doylestown, PA 18902, United States.

Funding

INSTITUTIONAL RESEARCH CANCER EPIDEMIOLOGY FELLOWSHIPT32CA009314 · NCI · JOHNS HOPKINS UNIVERSITY · PI Corinne E. Joshu, Meghan Bridgid Moran · 1985 to 2026
$11.2M
NCI NIH HHS T32 CA009314
6 · The paper itself

Abstract

backgroundCurrent antiviral treatment for chronic hepatitis B can suppress viral replication and reduce the risk of cirrhosis and liver cancer. It requires lifelong daily medication, and long-term adherence is often cited as a concern when initiating treatment. Hepatitis B treatment adherence in the context of the patient's medical and life experiences remains underexplored.

aimTo evaluate factors associated with adherence to hepatitis B oral antiviral treatment.

methodsA global online survey was administered anonymously to adults (aged 18 years or older) living with chronic hepatitis B. A subsample of 614 individuals who reported being on hepatitis B treatment was included in the analysis. Indices for treatment affordability, healthcare service acceptability, and individual physical, psychological, and emotional functioning were constructed (Cronbach's alpha = 0.71-0.83). Data analysis was conducted using Stata/BE 17.0.

resultsOverall, 81% of respondents reported high adherence to hepatitis B treatment. Lower adherence was observed among individuals who identified as African or African American (

conclusionFindings demonstrate high treatment adherence, although access to and acceptability of healthcare services, as well as an individual's physical functioning challenges, appear to be related to low adherence.

Indexed as

AccessibilityAdherenceAffordabilityAntiviral treatmentChronic hepatitis B

Identifiers

PMID41479582
PMCPMC12754545

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.