SynthesisFrontiers in neurology2025
Effects of aerobic exercise interventions on cognitive function, sleep quality, and quality of life in older adults with mild cognitive impairment: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy and certainty of evidence of exercise interventions for cognitive outcomes in older adults with mild cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in aging neuroscience · 2026Pooled it
- Review
- Acute Effects of High-Velocity Interval Cycling Versus Continuous Moderate-Intensity Cycling on Cognitive Function in Patients with Mild Cognitive Impairment.Brain sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Aerobic exercise, as a non-pharmacological intervention, has been widely recognized for its potential benefits on cognitive function in individuals with mild cognitive impairment (MCI). However, systematic evidence regarding its effects on other critical health domains, such as sleep quality and quality of life, remains limited. Moreover, previous meta-analyses have typically included a relatively small number of randomized controlled trials (RCTs), which may constrain the generalizability and objectivity of their findings. Objective: This study aimed to evaluate the effects of aerobic exercise on cognitive function, sleep quality, and quality of life in older adults with MCI, and to identify key exercise prescription parameters based on the FITT principle (frequency, intensity, time, and type). Results: A total of 26 randomized controlled trials involving 2,085 individuals with MCI were included. The meta-analysis revealed that aerobic exercise had a statistically significant positive effect on global cognitive function (SMD = 0.81, 95% CI: 0.58-1.05, Conclusion: The findings of this study demonstrate that aerobic exercise may significantly improve cognitive function and quality of life in older adults with MCI, with enhanced effects observed when intervention parameters are optimized. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024495979, Unique Identifier: CRD42024495979.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.