ReviewWorld journal of gastroenterology2025
Application of stem cells in the precise diagnosis and treatment of liver diseases.
Review in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver diseases caused by diverse inflammation or cancer have serious damaged people's physical and mental health and become a heavy social burden. Stem cells possess unique properties of self-renewal and multi-directional differentiation, which are widely used for disease remodeling and regenerative medicine. Of them, human induced pluripotent stem cell-based liver organoids with self-organization of sinusoidal vessels have been reported for diverse liver cancer remodeling and drug sensitivity test, which provide unique platforms to dissect functional consequences of diverse levels of heteroplasmy of target gene mutation in liver cancers. Meanwhile, mesenchymal stem/stromal cells have been adopted for clinical treatment research on various liver diseases, including acute liver injury, decompensated liver cirrhosis, hepatic fibrosis and acute-on-chronic liver failure. In this review article, we mainly focus on the state-of-the-art literatures upon stem cell-based disease modeling and cell therapy for multifarious liver diseases from the view of basic research and clinical progress, which will provide references for the development of stem cell-based regenerative medicine in the precise diagnosis and treatment of liver diseases.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.