Evidence map›Paper›PMID 41479668›Full record

ArticleFrontiers in nutrition2025

Postbiotics in pediatric clinical practice: position paper from Special Group of Latin American Society of Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN).

Rodrigo Vázquez-Frias, Gabriel Vinderola, Ana Teresa Abreu Y Abreu, Diana Angulo, Natasha Giler-Párraga, Liliana Ladino, Carolina Ortiz, Sebastián Pereira, Juan Pablo Bustamante

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07758933 (Prospective Study on the Safety of the Postbiotic Lactobacillus LB), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07758933 phase1 / phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective Study on the Safety of the Postbiotic Lactobacillus LB (Lactéol®) in Immuocompromised Pediatric Patients With Diarrhoeal Disease Treated at the Federico Gómez Children's Hospital of Mexico.

TypeinterventionalSponsorHospital Infantil de Mexico Federico GomezRan2026 to 2026Enrolled30ConditionsDiarrheaArmsLactobacillus LB
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rodrigo Vázquez-FriasLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Gabriel VinderolaInstituto de Lactología Industrial (UNL-CONICET), Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santa Fe, Argentina.
Ana Teresa Abreu Y AbreuSociedad Mexicana de Microbiota, Ciudad de México, Mexico.
Diana AnguloLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Natasha Giler-PárragaLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Liliana LadinoLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Carolina OrtizLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Sebastián PereiraLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.
Juan Pablo BustamanteLatin American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postbiotics, defined by the ISAPP as preparations of inanimate microorganisms and/or their components that confer health benefits, represent a promising category of microbiome-derived solutions. This position paper highlights their clinical relevance, particularly in pediatrics, while addressing key aspects of definition, safety, quality, and strain-level specificity. Evidence supports the use of

Indexed as

clinical practiceinactivated microorganismsmicrobiomepediatricpostbiotics

Identifiers

PMID41479668
PMCPMC12755150

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.