Evidence mapPaperPMID 41479831Full record

ArticleWorld journal of nephrology2025

Kidney transplant outcomes in obese pediatric patients.

Guido Gembillo, Lorenzo Lo Cicero, Domenico Santoro

Abstract readEditorial
In one paragraph

Article in World journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guido GembilloUnit of Nephrology and Dialysis, AOU "G. Martino", University of Messina, Messina 98125, Sicilia, Italy. ggembillo@gmail.com.
Lorenzo Lo CiceroDepartment of Clinical and Experimental Medicine, University of Messina, Messina 98121, Sicilia, Italy.
Domenico SantoroUnit of Nephrology and Dialysis, AOU "G. Martino", University of Messina, Messina 98125, Sicilia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of pediatric obesity has raised numerous questions about its health implications, particularly regarding renal transplant outcomes. These complications often hinder medical interventions in these children. While kidney transplants are often viewed from an organocentric perspective, the overall health of the patient is critical to the success of the procedure. Current discussions make it clear that childhood obesity poses significant problems not only for graft survival, but also for long-term overall health. Childhood obesity can lead to many metabolic disorders such as diabetes and hypertension. These conditions can significantly affect a child's suitability for a transplant or make the process more difficult. A child's weight can affect the pharmacokinetics of drugs used to prevent organ rejection. Obesity impacts the individual and sets in motion a cascade of effects that can jeopardize transplant success and recovery, so understanding is needed. Research on graft survival rates is both optimistic and concerning. Clinical studies show that obese children often have an increased risk of post-transplant complications, which affects transplant longevity. The likelihood of rejection may increase due to the metabolic status of an obese child. Due to the allocation of healthcare resources for the treatment of obesity-related diseases, availability for the transplant itself may be limited. Many children maintain an adequate quality of life after a kidney transplant, but excessive weight can significantly affect their health and chances of survival. The main target is looking for highly successful strategies to give all children who need a transplant a better future, regardless of their weight.

Indexed as

Bariatric surgeryChronic kidney diseaseDiabetesKidney transplantNutritionNutritional therapyObesityPediatric patientsRenal replacement therapiesRenal transplantation

Identifiers

PMID41479831
PMCPMC12754410

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.