SynthesisFrontiers in public health2025
Effect of tele-rehabilitation guided intervention on pain and function in middle-aged and older adult patients with knee osteoarthritis: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- [Study on the effect of superficial layer damage on cartilage retention performance].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To assess the effect of tele-rehabilitation interventions on pain and function in middle-aged and older adult patients with knee osteoarthritis (KOA). Methods: A systematic search of randomized controlled trials (RCTs) was conducted in the EMBASE, PubMed, Cochrane Library, and Web of Science databases, covering the period from 2006 to 31 August 2025. Screening criteria were developed based on the PICOS principle. The Cochrane Risk of Bias Assessment Tool (RoB 2) was used to evaluate the quality of the literature, and meta-analysis was performed using STATA 15.0 software. Results: A total of 12 RCTs involving 1,151 patients were included. The results showed that tele-rehabilitation was effective in VAS Pain (SMD = -0.57, 95% CI: -1.25-0.10), WOMAC pain (SMD = -0.08, 95% CI: -0.98-0.83), WOMAC function (SMD = -0.44, 95% CI: -0.88-0.00), and KOOS total (SMD = 0.52, 95% CI: -0.37-1.40), showing a trend toward improvement, but none reached statistical significance except for WOMAC function score. Sensitivity analyses showed robust results, and Egger's test did not reveal significant publication bias. Conclusion: Tele-rehabilitation shows positive trends in pain and functional improvement in middle-aged and older adult patients with KOA; however, current evidence is insufficient to demonstrate significant superiority. Given its good accessibility, tele-rehabilitation can be used as a complementary modality to traditional rehabilitation. More high-quality studies are needed to clarify its optimal intervention protocol and long-term efficacy. Systematic review registration: PROSPERO (registration number: CRD420251137582).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.