SynthesisWorld journal of gastroenterology2025
Exploring exercise modalities and their impact on inflammatory bowel disease: A systematic review of rodent colitis models.
Synthesis in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- No impact of sex or testosterone treatment on wheel running in a rat model of inflammatory bowel disease.Biology of sex differences · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLifestyle factors are closely associated with the onset and progression of inflammatory bowel disease (IBD). Studies have demonstrated the positive effects of exercise on clinical outcomes and quality of life in individuals with IBD. Despite the well-documented role of exercise in improving IBD outcomes, the underlying mechanisms remain unclear.
aimTo compare the efficacy of different exercise modalities and explore their potential physiological mechanisms in rodent models of colitis.
methodsWe conducted a comprehensive search of five databases from inception to September 24, 2024, which yielded 19 animal studies in rodent colitis models. We compared the efficacy of various forms of exercise and explored the possible physiological mechanisms. The effects of different exercise modalities, namely forced treadmill running (FTR), voluntary wheel running (VWR), swimming, climbing, and jumping, on both macroscopic symptoms (
resultsVWR (simulated recreational physical activity), swimming (aerobic exercise), and strength training (climbing and jumping) consistently promoted overall health in animal colitis models. However, evidence for FTR remains inconsistent, with a notable number of studies suggesting potential exacerbation of colitis symptoms, possibly due to stress or fatigue resulting from its coercive nature. Overall, various exercise (
conclusionExercise modality is critical in influencing colitis outcomes, with voluntary and low-stress forms generally being beneficial, while forced exercise may yield adverse effects. These findings highlight the importance of exercise type and individual tolerance in designing therapeutic exercise interventions for IBD. Further research is warranted to establish a robust therapeutic framework for exercise-based interventions in IBD management.
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