Evidence map›Paper›PMID 41482363›Full record

ArticleIn vivo (Athens, Greece)

Low-temperature

Tadas Korzinskas, Reiner Schnettler, Denis Rimashevskiy, Birzhan Malik, Baurzhan Dakenov, Diana Bagdoniene, Ole Jung, Mike Barbeck

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tadas KorzinskasDepartment of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Institute for Dental and Craniofacial Sciences, Benjamin Franklin Charité Campus, Berlin, Germany.
Reiner SchnettlerUniversity Medical Centre, Justus Liebig University of Giessen, Giessen, Germany.
Denis RimashevskiyDepartment of Traumatology and Orthopedics, Peoples Friendship University of Russia, Moscow, Russian Federation.
Birzhan MalikDepartment of Traumatology and Orthopedics, Astana Medical University, Astana, Kazakhstan.
Baurzhan DakenovLeader Stom LLP, Astana, Kazakhstan.
Diana BagdonieneDepartment of Traumatology and Orthopedics, Astana Medical University, Astana, Kazakhstan.
Ole JungClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.
Mike BarbeckClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany mike.barbeck@med.uni-rostock.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMaxillary sinus floor elevation is a well-established procedure for increasing bone volume in the posterior maxilla, yet the regenerative outcome depends strongly on the choice of grafting material. This clinical study compared a high-temperature sintered xenograft (Bio-Oss PATIENTS AND

methodsEight patients underwent split-mouth sinus augmentation with both materials, and biopsies were retrieved at 6 months after implant placement. Histological, histomorphometrical, and immunohistochemical analyses were performed to assess bone formation, material resorption, and tissue compatibility. Immunohistochemistry was applied to evaluate the local immune response, focusing on macrophage polarization and multinucleated giant cell activity. Quantitative histomorphometry determined the relative areas of newly formed bone, residual graft material, and connective tissue.

resultsHistopathological and histomorphometrical analyses demonstrated comparable levels of new bone formation in both groups, confirming reliable osteoconduction. Immunohistochemical evaluation revealed tartrate-resistant acid phosphatase isoform 5a (TRAP5A) expression in multinucleated giant cells adherent to both materials. Interestingly, Bio-Oss

conclusionThese findings indicate that although both xenogeneic substitutes (Bio-Oss

Indexed as

Bone RegenerationBone SubstitutesSinus Floor AugmentationAdultAgedFemaleHumansMacrophagesMaleMiddle AgedMineralsOsteogenesisTemperatureTitaniumBio-OssBone SubstitutesMineralsTitaniumbone regenerationmacrophage polarizationMaxillary sinus floor elevationosteoimmunologyxenogeneic bone substitute

Identifiers

PMID41482363
PMCPMC12764260

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.