Evidence map›Paper›PMID 41483113›Full record

ArticleJournal of community genetics2026

Strategies to build trustworthiness and increase diversity in colorectal cancer biospecimen research: a multi-phase, multi-site qualitative study.

Kristi L Roybal, Brett Nava-Coulter, Jane Roberts, Destiny Harden, Saul Castro, Anna Revette, Maria Connolly, Gina Johnson, Jennifer A Rountree, Suzanne Brodney and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kristi L RoybalHealth Research Accelerator, Providence Research Network, 4400 NE Halsey St. Building 2 Suite 300-09, Portland, OR, 97213, USA. kristi.roybal@providence.org.
Brett Nava-CoulterSurvey and Qualitative Methods Core, Dana Farber Cancer Institute, Boston, MA, USA.
Jane RobertsSurvey and Qualitative Methods Core, Dana Farber Cancer Institute, Boston, MA, USA.
Destiny HardenClinical Translational and Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.
Saul CastroHealth Research Accelerator, Providence Research Network, 4400 NE Halsey St. Building 2 Suite 300-09, Portland, OR, 97213, USA.
Anna RevetteSurvey and Qualitative Methods Core, Dana Farber Cancer Institute, Boston, MA, USA.
Maria ConnollyHealth Research Accelerator, Providence Research Network, 4400 NE Halsey St. Building 2 Suite 300-09, Portland, OR, 97213, USA.
Gina JohnsonGreat Plains Tribal Leaders Health Board, Rapid City, SD, USA.
Jennifer A RountreeHealth Research Accelerator, Providence Research Network, 4400 NE Halsey St. Building 2 Suite 300-09, Portland, OR, 97213, USA.
Suzanne BrodneyDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
Kimberly SchoolcraftFight Colorectal Cancer, Springfield, MO, USA.
David A DrewClinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Folasade P MayDepartment of Medicine, David Geffen School of Medicine, UCLA Ronald Reagan Medical Center, University of California Los Angeles, Los Angeles, CA, USA.
Jennifer S HaasDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
Erica T Warner *Clinical Translational and Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.
Staci J Wendt *Health Research Accelerator, Providence Research Network, 4400 NE Halsey St. Building 2 Suite 300-09, Portland, OR, 97213, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlack, Latino, and American Indian individuals are underrepresented in biospecimen research. Obtaining biospecimens from these populations is particularly relevant for understanding, preventing, and treating colorectal cancer and translating those insights to eliminate persistent racial and ethnic inequities in colorectal cancer. The aim of this qualitative study was to identify information needs and culturally appropriate approaches to biorepository recruitment among Black, Latino, and American Indian patients and community members.

methodsWe used a multi-phase, multi-site design that included key informant interviews and focus groups with patients and community members in Los Angeles, Boston, and South Dakota. We analyzed interview data using rapid qualitative analysis and focus group data using reflexive thematic analysis.

resultsWe interviewed 10 keys informants with expertise in the recruitment of racially and ethnically diverse participants into biospecimen research and facilitated 21 focus groups with a 101 patients and community members who identified as Black, Latino, or American Indian. We generated six themes from our analyses that we organized into a best practices framework for building trustworthiness and increasing diversity in biospecimen research: (1) cultural responsiveness and inclusivity; (2) community-based partnerships; (3) convenience and accessibility; (4) meaningful and compelling purpose; (5) mindful incentives; and (6) trusted messengers and information sharing. DISCUSSION: Our findings provide insight into the factors that influence Black, Latino, and American Indian individuals' decisions to participate in biorepositories. The best practices framework developed from this study presents actionable strategies researchers can adopt to build trustworthiness and increase diversity in colorectal cancer biospecimen research.

Indexed as

BiorepositoriesBiospecimen researchColorectal cancer inequitiesUnderrepresented populations

Identifiers

PMID41483113
PMCPMC12764713

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.