Evidence map›Paper›PMID 41483126›Full record

ArticleJournal of assisted reproduction and genetics2026

Predictors of referral for fertility preservation counseling in patients diagnosed with cancer.

Paris N Chey, Miranda L M Delwalla, Julia Shuford, Natalie Albright, Katharina Goebel, Julia Grigorian, Sheila Rajagopalan, D Austin Schirmer, Heather S Hipp

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paris N CheyEmory University School of Medicine, Atlanta, GA, USA. paris.chey@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0003-4300-6974
Miranda L M DelwallaDivision of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
Julia ShufordEmory University School of Medicine, Atlanta, GA, USA.
Natalie AlbrightEmory University School of Medicine, Atlanta, GA, USA.
Katharina GoebelEmory University School of Medicine, Atlanta, GA, USA.
Julia GrigorianEmory University School of Medicine, Atlanta, GA, USA.
Sheila RajagopalanEmory University School of Medicine, Atlanta, GA, USA.
D Austin SchirmerDivision of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
Heather S HippDivision of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFertility preservation (FP) is an important aspect of care for reproductive-aged cancer patients since treatment can significantly impact fertility. Despite professional recommendations for early referral to FP, rates remain low. This study evaluates predictors of FP referrals by Oncologists to Reproductive Endocrinology and Infertility (REI) physicians among reproductive-aged cancer patients at a large academic institution. MATERIALS AND

methodsThis cross-sectional study evaluated patients ages 14-42 years seen by an Oncologist from 2022 to 2024 with a new diagnosis of cancer for whom planned treatment is either gonadotoxic or requires delayed pregnancy. Referral rates to REI physicians were assessed by patient demographics and cancer and Oncologist characteristics as potential predictors. Statistical analysis used chi-square tests, Fisher's exact tests, and multivariable logistic regression.

resultsOf 510 patients seen by an Oncologist for a newly diagnosed cancer, only 127 (22.5%) were referred for FP. Patients > 30 years were less likely to be referred than younger patients (aOR = 0.15, 95% CI = 0.05, 0.47, p = 0.001). Patients with breast cancer were most likely to be referred compared to other cancers. There was no difference in referral rates by physician gender. Physicians with 21-30 years of experience were more likely to refer than those with < 10 years (aOR = 2.89, 95% CI = 1.50, 5.62, p = 0.002).

conclusionsThere was a low rate of FP referral and significant disparities based on patient demographics and clinical factors. Referral rates were higher among younger patients and breast cancer patients. Standardizing FP referrals across oncology specialties, consideration of electronic health record "soft stops" for referral and increasing patient and provider education are essential to improving referral rates.

Indexed as

CounselingFertility PreservationNeoplasmsReferral and ConsultationAdolescentAdultCross-Sectional StudiesFemaleHumansMalePregnancyYoung AdultCancerFertility preservationOncofertilityReproductive healthSurvivorship

Identifiers

PMID41483126
PMCPMC12982817

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.