Trial reportEuropean radiology2026
Digital variance angiography enables up to 80% reduction in stationary acquisition radiation dose during prostatic artery embolization: a prospective randomized trial.
Trial report in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography.Circulation. Cardiovascular interventions · 2026Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
objectivesDigital variance angiography (DVA) has demonstrated superior image quality compared to digital subtraction angiography (DSA), but its potential remains underexplored for complex procedures. MATERIALS AND
methodsThis prospective randomized controlled trial enrolled 70 patients (mean ± SD age: 69.23 ± 8.7, range 53-96) undergoing PAE between January and October 2023. Patients were randomized to normal dose (ND) DSA (n = 35) or ultra-low dose (ULD) DSA (n = 35), with the latter reducing target detector dose by 72% for stationary acquisitions only. Radiation dose analysis was limited to stationary acquisitions, as only these series were acquired using the modified low-dose protocol. Dose-area product (DAP), contrast-to-noise ratios (CNR), and visual image quality of DSA and DVA images were compared. Three experienced interventional radiologists conducted a randomized, blinded 5-point Likert evaluation of large and small vessels, tissue blush, and background noise. Statistical analysis included Mann-Whitney tests, Spearman correlation, Kendall Tau B, and Bangdiwala's B for interrater agreement.
resultsThe ULD protocol reduced stationary acquisition-related DAP by up to 80% compared to controls (580 ± 66 vs 2872 ± 396 µGym²/patient, p < 0.001). DVA showed significantly higher CNR in both groups, with median CNR
conclusionDVA enables substantial radiation dose reduction in PAE while maintaining superior image quality versus DSA, potentially improving angiographic safety and efficacy. KEY POINTS: Question DVA is useful in reducing dose and enhancing image quality, yet it was not validated for complex angiographic procedures. Findings DVA provides better qualitative and quantitative image quality than DSA with reduced dose for prostatic artery embolizations. Clinical relevance DVA significantly improves image quality in Prostatic Artery Embolization compared to DSA, which allows up to 80% reduction in radiation burden to patients and interventionalists alike, while it also maintains diagnostic image quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.