Evidence map›Paper›PMID 41484521›Full record

ArticleThe international journal of cardiovascular imaging2026

Relationship of cardiac MRI-derived pulmonary arterial stiffness markers and invasive hemodynamic.

Ipek Buber, Paul Heerdt, Inderjit Singh, Joseph Phillip, Cihan Ilyas Sevgican, Jérôme Lamy, Jie Xiang, Dana C Peters

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In one paragraph

Article in The international journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ipek BuberDepartment of Cardiology, Pamukkale University, Denizli, Turkey. dr.ipekbuber@gmail.com.
Paul HeerdtDepartment of Internal Medicine, Cardiovascular Division, Yale University, New Haven, CT, USA.
Inderjit SinghDepartment of Internal Medicine, Cardiovascular Division, Yale University, New Haven, CT, USA.
Joseph PhillipDepartment of Pulmonary, Critical Care and Sleep Medicine, Yale University, New Haven, CT, USA.
Cihan Ilyas SevgicanDepartment of Emergency, Private Health Hospital, Denizli, Turkey.
Jérôme LamyService de Radiology, Hospital European Georges- Pompidou, AP-HP, Université de Paris-Cité, Paris, France.
Jie XiangDepartment Biomedical Engineering, Yale University, New Haven, CT, USA.
Dana C PetersDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial stiffness (PAS) is a noninvasive imaging biomarker associated with disease severity in pulmonary hypertension (PH). This study aimed to evaluate PAS using cardiac magnetic resonance (CMR) imaging and investigate its relationship with hemodynamic parameters from right heart catheterization (RHC) across PH subgroups. In this retrospective study, 44 patients with PH who underwent both RHC and CMR were classified into pre-capillary (precapPH), post-capillary (postcapPH), and combined pre- and post-capillary (combPH) PH groups based on guideline-defined criteria. PAS was assessed by CMR-derived pulse wave velocity (PWV) and relative area change (RAC) of the main pulmonary artery. RHC measurements included mPAP, PVR, and right ventricular pressures and mixed venous saturation. PWV was significantly higher in combPH (4.49 ± 1.32 m/s) compared to precapPH (3.40 ± 0.98 m/s, p = 0.04). RAC was significantly lower in combPH (0.18 ± 0.11) than in postcapPH (0.28 ± 0.09), p = 0.01) and precapPH (0.18 ± 0.07, p = 0.01). PWV correlated with mPAP (r = 0.34, p = 0.022), RAP (r = 0.39, p = 0.008), and RVEDVi (r = 0.34, p = 0.022), while RAC showed a negative correlation with PVR (r = - 0.36, p = 0.01). Distinct RV adaptation patterns were observed among subgroups, with combPH patients exhibiting the most impaired hemodynamics. CMR-derived PAS indices correlate with invasive hemodynamic markers and differ among PH subtypes. PWV and RAC may serve as useful noninvasive markers for assessing pulmonary vascular burden and differentiating disease severity in PH. Larger prospective studies are needed to validate their clinical utility.

Indexed as

Phase-contrastPulmonary arterial stiffnessPulmonary hypertensionPulse wave velocity

Identifiers

PMID41484521

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.