Evidence map›Paper›PMID 41484877›Full record

ArticleBMC public health2026

The mediating and moderating roles of physical sub-health in the relationship between family functioning and mental health problems among Chinese adolescents.

Yunan Zhang, Xuanyi Cai, Guangxiang Jiang, Wenjie Xu, Yu Ran, Dongran Han, Hongjuan Wen, Yixing Liu

Abstract read
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yunan ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xuanyi CaiSchool of Management, Beijing University of Chinese Medicine, Beijing, 102488, China.
Guangxiang JiangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Wenjie XuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yu RanSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China.
Dongran HanSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, 102488, China. handongr@gmail.com.
Hongjuan WenSchool of Management, Changchun University of Traditional Chinese Medicine, Changchun, 130117, China. wenhj@ccucm.edu.cn.
Yixing LiuSchool of Management, Beijing University of Chinese Medicine, Beijing, 102488, China. yixingliu1987@gmail.com.

Funding

Beijing University of Chinese Medicine 2022-JYB-JBZR-021National Natural Science Foundation of China (NSFC) Youth Project 82205315
6 · The paper itself

Abstract

backgroundAdolescent mental health is shaped by both family environments and physical well-being. However, the role of physical sub-health, a state of functional imbalance and fatigue prior to diagnosable illness, remains poorly understood in this process. This study examined whether physical sub-health serves both as a psychosomatic pathway and as a vulnerability factor linking family functioning to adolescent mental health.

methodsA cross-sectional survey was conducted among 647 primary and secondary school students across China. Validated scales were used to assess family functioning, physical sub-health (operationalized based on constitution characteristics), and mental health symptoms. Structural equation modeling (SEM) was employed to examine the mediating role of physical sub-health. Furthermore, latent moderated structural equation modeling (LMS) was applied to test its moderating effect.

resultsPhysical sub-health significantly mediated the association between family functioning and mental health, with the largest indirect effects observed for qi stagnation (β = -0.27, 95% CI [-0.36, -0.20]), qi deficiency (β = -0.13, 95% CI [-0.17, -0.10]), and phlegm dampness (β = -0.12, 95% CI [-0.15, -0.08]). These findings suggest that functional bodily imbalance may help explain how family stress is related to emotional and behavioral difficulties. In addition, physical sub-health moderated this association, with adolescents showing poorer physical resilience being more susceptible to the detrimental effects of dysfunctional family environments.

conclusionPhysical sub-health plays a dual psychosomatic role in how family functioning relates to adolescent mental well-being, acting as both a mechanism and a vulnerability factor. These findings highlight the potential value of integrated public health strategies that combine family support, school-based identification of psychosomatic risk, and routine health promotion to strengthen youth psychosomatic resilience.

trial registrationThe study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board (or Ethics Committee) of Ethics Committee of Beijing University of Chinese Medicine (protocol code No: 2023BZYLL1101 and date of approval: 2023.11.10).

Indexed as

Adolescent HealthBody ConstitutionEast Asian PeopleFamily RelationsMental DisordersAdolescentChinaCross-Sectional StudiesEatingFemaleHumansMaleMediation AnalysisMental HealthQiYang DeficiencyAdolescentsFamily functioningMediation modelMental health problemsModeration modelPhysical sub-health

Identifiers

PMID41484877
PMCPMC12866022

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.