Evidence map›Paper›PMID 41484993›Full record

ReviewBiology direct2026

Organelle-specific regulation of ferroptosis.

Yu Zhang, Mengyan Liu, Min Li, Yile Wu, Mi Xie, Xiaolong Liu, Haodong Lu, Xiaoyan Zhai, Yanling Yang

Abstract readReview
In one paragraph

Review in Biology direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu ZhangYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China.
Mengyan LiuYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China.
Min LiYan'an University Affiliated Hospital, Yan'an, Shaanxi, 716000, P.R. China.
Yile WuYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China.
Mi XieYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China.
Xiaolong LiuYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China.
Haodong LuYan'an University Affiliated Hospital, Yan'an, Shaanxi, 716000, P.R. China. yadxfyhd@163.com.
Xiaoyan ZhaiYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China. zhaixy@yau.edu.cn.
Yanling YangYan'an Medical College, Yan'an University, Yan'an, Shaanxi, 716000, P.R. China. yangyanling8889@163.com.

Funding

General Project of Shaanxi Provincial Department of Science and Technology (2024SF-YBXM-037)National Natural Science Foundation of China funded project 82360223National Natural Science Foundation of China funded project 82560280
6 · The paper itself

Abstract

Ferroptosis, an iron-dependent form of regulatory cell death driven by lipid peroxidation, has emerged as a key factor in several pathological conditions. At the organelle level, ferroptosis involves complex interactions between mitochondria, lysosome, endoplasmic reticulum (ER), Golgi apparatus, Nucleus, autophagosome, lipid droplet and peroxisome. Each of them plays a unique role in the ferroptosis cascade. Although the molecular mechanisms of ferroptosis have been extensively studied, the role of specific organelles in this process has not been fully explored. This review aims to summarize the latest advances in organelle-level changes during ferroptosis.

Indexed as

FerroptosisOrganellesAnimalsEndoplasmic ReticulumHumansLipid PeroxidationMitochondriaCell deathFerroptosisLipid peroxidationOrganelle crosstalkTargeted therapy

Identifiers

PMID41484993
PMCPMC12853712

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.