Evidence map›Paper›PMID 41486091›Full record

ArticleMagnetic resonance in medicine2026

Pole-To-Pole 3D Radial Trajectory Designs Improve Image Quality and Quantitative Parametric Mapping in the Brain and Heart.

Eva S Peper, Grzegorz Bauman, Matteo Tagliabue, Berk C Açikgöz, Nils M J Plähn, Adèle L C Mackowiak, Yasaman Safarkhanlo, Joseph G Woods, Davide Piccini, Li Feng and 3 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Simultaneous TMagnetic resonance in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Eva S PeperDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Grzegorz BaumanDivision of Radiological Physics, Department of Radiology, University Hospital Basel, Basel, Switzerland.
Matteo TagliabueDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0009-0001-2142-8917
Berk C AçikgözDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Nils M J PlähnDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0009-0002-2624-5412
Adèle L C MackowiakDepartment of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Yasaman SafarkhanloTranslational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland.ORCID 0000-0001-9573-870X
Joseph G WoodsDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Davide PicciniScientific Collaborations and Strategic Partnerships, Siemens Healthcare Srl, Milano, Italy.
Li FengCenter for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York University, New York, USA.ORCID 0000-0002-8692-7645
Christopher W RoyDepartment of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Oliver BieriDivision of Radiological Physics, Department of Radiology, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-6755-5495
Jessica A M BastiaansenDepartment of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-5485-1308

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PCEFP2_194296
6 · The paper itself

Abstract

purposeTo design 3D radial spiral phyllotaxis trajectories aimed at removing phase inconsistencies, improving image quality, and enhancing parametric mapping accuracy by acquiring nearly opposing spokes starting from both hemispheres in 3D radial k-space.

methodsTwo 3D radial trajectories, pole-to-pole and continuous spiral phyllotaxis, were developed and implemented on a 3T MRI scanner in a phase-cycled balanced steady-state free precession (bSSFP) and a spoiled gradient-echo (GRE) sequence. Image quality and k-space center phase variations were evaluated in a spherical phantom using the original and new radial phyllotaxis designs. T1/T2 was quantified and compared using phase-cycled bSSFP data acquired with the new radial trajectory designs, as well as the original phyllotaxis trajectory and a Cartesian trajectory as references, in both an MRI system phantom and the brains of three healthy volunteers. ECG-triggered whole-heart GRE data were acquired using the original and pole-to-pole phyllotaxis trajectories in three healthy volunteers and compared for image quality improvement.

resultsAll 3D radial trajectory designs showed variations in the k-space center phase depending on the orientation of the readout spokes. Image quality improved when using the pole-to-pole and continuous phyllotaxis over the original trajectory. Scans using the original trajectory had higher T1/T2 estimation errors in comparison to the new trajectories and the Cartesian trajectory. The pole-to-pole and continuous trajectories improved T1/T2 maps of the brain and image quality for all cardiac images.

conclusionAcquiring nearly opposing spokes in 3D radial trajectory designs compensates phase inconsistencies without requiring additional corrections, which improves quantitative imaging and anatomical visualizations.

Indexed as

BrainHeartImaging, Three-DimensionalMagnetic Resonance ImagingAdultAlgorithmsHealthy VolunteersHumansImage Processing, Computer-AssistedPhantoms, ImagingReproducibility of Results

Identifiers

PMID41486091
PMCPMC12962215

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.