ArticleJournal of thoracic imaging2026
Diagnostic Significance of Phase-Resolved Functional Lung Low-field Magnetic Resonance Imaging in Comparison to Photon-Counting CT and Pulmonary Function Tests in Connective Tissue Disease-associated Interstitial Lung Diseases.
Article in Journal of thoracic imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe diagnosis of connective tissue disease-associated interstitial lung diseases (CTD-ILD) is connected to radiation exposure due to periodical CT scans. This study aims to investigate the alternative imaging method, Phase-Resolved Functional Lung (PREFUL), regarding its performance in low-field MRI. A comparison of PREFUL, photon-counting CT (PCCT) and pulmonary function tests (PFT) was performed to identify correlations that could restructure the diagnostics of CTD-ILD. MATERIALS AND
methodsIn this prospective single-center study, free-breathing PREFUL acquisitions of CTD-ILD patients were done after clinically indicated PCCT imaging. The severity and extent of CTD-ILD in PCCT were assessed via the Warrick score and used as a reference. Spearman's correlation coefficient ( r ) was calculated to examine the association between PREFUL, PCCT, and PFT.
resultsThe data of 31 CTD-ILD patients (64.32±12.36 y, 10 men) were evaluated. Most correlations of PREFUL parameters with PFT were found with the Tiffeneau-Pinelli index (FEV1/FVC). The Warrick score showed excellent inter-rater agreement and correlations ( P <0.05) with the PFT parameters forced vital capacity (FVC) and the diffusing capacity of the lung for carbon monoxide corrected for hemoglobin (DLCOc) [FVC: r =-0.43, DLCOc SB: r =-0.65, DLCOc/VA: r =-0.50]. No correlation was found between PREFUL parameters and PCCT.
conclusionsThe feasibility of PREFUL using low-field MRI was demonstrated in patients with CTD-ILD. Several correlations between PREFUL and PFT parameters were found, indicating that MRI can quantify lung function impairment. Nevertheless, CT remains the gold standard for CTD-ILD assessment and further research in PREFUL is needed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.