ArticleACS omega2025
Identifying a Novel BCL2L1-Targeting Peptide from Porcine Placenta for Lymphoma Therapy.
Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents a comprehensive in silico framework, integrating network pharmacology, molecular docking, survival analysis, and pharmacokinetic profiling, to identify and prioritize bioactive porcine placenta peptides for lymphoma therapy. Initial protein-protein interaction (PPI) network analysis identified BCL2L1, CASP3, and NFKB1 as key hub proteins, with pathway enrichment analysis highlighting their significant involvement in apoptosis and the sphingolipid signaling pathway. Validating their clinical relevance, survival analysis in an Acute Myeloid Leukemia (AML) cohort confirmed that high expression of BCL2L1 (HR = 0.79,
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.