Evidence map›Paper›PMID 41487455›Full record

ReviewGastro hep advances2026

Endohepatology: Evolving Indications, Challenges, Unmet Needs and Opportunities.

Akash Roy, Mithun Sharma, Anand V Kulkarni, Sundeep Lakhtakia, Aniruddha Pratap Singh, Rakesh Kalapala, Gregory G Ginsberg, D Nageshwar Reddy, K Rajender Reddy

Abstract readReview
In one paragraph

Review in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akash RoyInstitute of Gastrosciences and Liver Transplantation, Apollo Multispeciality Hospitals, Kolkata, India.
Mithun SharmaDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Anand V KulkarniDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Sundeep LakhtakiaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Aniruddha Pratap SinghDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Rakesh KalapalaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Gregory G GinsbergDivision of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, Pennsylvania.
D Nageshwar ReddyDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
K Rajender ReddyDivision of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endohepatology provides a unison of 2 rapidly developing fields of hepatology and advanced endoscopy. Conventionally, endoscopy in liver disease was restricted primarily to the management of varices. However, multiple new domains have emerged in advanced endoscopy, driven mainly by endoscopic ultrasound (EUS), and as such find several applications in clinical hepatology. Robust data have emerged regarding EUS liver biopsy and the management of gastric varices, and are becoming the first line of care at experienced centers. EUS-guided portal pressure gradient and direct measurements appear to be an exciting frontier for portal pressure assessment. EUS shear wave elastography holds promise but needs standardization and comparison to well-established noninvasive surrogates. Endobariatrics opens up new avenues in optimizing comprehensive obesity management. Interesting crossroads emerge in liver transplantation, where endohepatology may provide a unique single setting investigation and therapeutic solution. Several other potential uses are emerging but need to be replicated across settings. While the advancements usher in excitement, several gaps in knowledge and pragmatic concerns remain with the application of endohepatology, which need to be balanced against patient safety and in optimizing outcomes.

Indexed as

EndohepatologyGastric VaricesLiver BiopsyPortal Pressure

Identifiers

PMID41487455
PMCPMC12756639

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.