ReviewFrontiers in molecular biosciences2025
Methods for telomere length measurement: an update on current technologies and emerging approaches.
Review in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Genetic Determinants of Telomere Length and Their Role in Human Disease: Molecular Mechanisms and Underrepresented Populations' Perspectives.Biomedicines · 2026Review
- Nanoparticle-Based Tools to Study Hallmarks of Aging at the Molecular Level.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Telomeres are nucleoprotein complexes at chromosome ends, composed of tandemly repeated specific DNA sequences along with associated proteins. In somatic cells, telomeres progressively shorten with each cell division, making telomere length a key biomarker of cellular aging. Moreover, alterations in telomeric attrition are characteristic of numerous lifestyle factors, age-related diseases, and cancers, establishing telomere length as both a pivotal biomarker and a central focus in contemporary biomedical research. Strong interest in this area drives the continuous development of new methods for telomere length measurement and improvements to existing ones. Currently, over two dozen such methods have been developed, making the ability to select the most appropriate one essential for addressing specific research objectives. This review provides a state-of-the-art survey of all existing methods, highlighting their advantages, limitations, and applications. Special attention is focused on the rapidly evolving field of adapting long-read sequencing technologies to enhance the efficiency of telomere length measurement, along with novel insights into the structure and diversity of telomeric sequences uncovered by this approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.