Evidence map›Paper›PMID 41488310›Full record

SynthesisFrontiers in microbiology2025

The characteristics of the gut microbiota in patients with Kawasaki disease: a systematic review.

Hongbo Chen, Hanmin Liu, Lina Qiao, Yang Liu, Dan Yu, Zhiling Wang, Tao Wang, Weiran Li

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongbo ChenDepartment of Medical Genetics/Prenatal Diagnostic Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Hanmin LiuKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Lina QiaoKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Yang LiuKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Dan YuDepartment of Medical Genetics/Prenatal Diagnostic Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Zhiling WangKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Tao WangKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Weiran LiKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut-vascular axis has emerged as a critical focus of research, with accumulating evidence suggesting distinct alterations in intestinal microbiota among patients with Kawasaki disease (KD). However, no systematic review to date has comprehensively characterized gut microbial dysbiosis in this population. This systematic review aimed to investigate changes in the composition of gut microbiota in KD patients. A comprehensive search of MEDLINE, EMBASE, Web of Science, and the Cochrane Library databases was conducted, and the study quality was assessed using the Newcastle-Ottawa Scale. All reported taxa were re-annotated according to the SILVA 138 database. Seven studies were enrolled in our review. In acute-phase KD, reduced Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251148103.

Indexed as

childrengut microbiotagut-vascular axisIllumina sequencingKawasaki disease

Identifiers

PMID41488310
PMCPMC12756895

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.