Evidence map›Paper›PMID 41488342›Full record

ReviewPhotoacoustics2026

Photoacoustic imaging: An emerging tool for intraoperative margin assessment in breast-conserving surgery.

Zhijie Luo, Yiqiong Zheng, Ruixi Sun, Wenye Gong, Jiayu Wang, Guangwei Chen, Ye Zhang, Runqi Zhao, Daohuai Jiang, Fei Gao and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Photoacoustics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhijie LuoPLA General Hospital (PLA Medical School), Beijing 100853, China.
Yiqiong ZhengDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.
Ruixi SunSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230026, China.
Wenye GongCivil Aviation Medical Center Physical Examination and Appraisal Institute, Beijing 100123, China.
Jiayu WangDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.
Guangwei ChenDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.
Ye ZhangDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.
Runqi ZhaoDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.
Daohuai JiangKey Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350117, China.
Fei GaoSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230026, China.
Xiru LiDepartment of General Surgery, The First Medical Center of PLA General Hospital, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic Imaging (PAI) synergizes light's optical contrast with ultrasound's penetration depth via the photoacoustic effect. Breast cancer remains a global challenge, particular demanding precise intraoperative tumor demarcation during breast-conserving surgery (BCS). PAI has the potential to address this need by enabling boundary delineation, promoting complete resection and healthy tissue preservation. This review summarizes breast cancer epidemiology and BCS's clinical demands, highlighting PAI's unique advantages for intraoperative use. PAI can dynamically monitor cellular/tissue morphology, blood oxygen saturation, vasculature, and tumor-associated calcifications, generating high-contrast tumor margin information. This real-time feedback enhances surgical precision, reduces recurrence rates, and improves breast aesthetics and patient quality of life. Despite translational challenges, PAI is poised to become a revolutionary tool for optimizing BCS outcomes.

Indexed as

Breast cancerBreast-conserving surgeryPhotoacoustic imagingTumor margin assessment

Identifiers

PMID41488342
PMCPMC12757564

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.